Details
PSMD (peak width of skeletonized mean diffusivity) is a robust, fully-automated and easy-to-implement marker for cerebral small vessel disease based on diffusion tensor imaging, white matter tract skeletonization (as implemented in FSL-TBSS) and histogram analysis.
PSMD has been validated in several samples with cerebral small vessel disease. PSMD outperformed conventional imaging markers (white matter hyperintensity volume, lacune volume, microbleed number and brain volume) in several aspects. PSMD also had the highest inter-scanner reliabilty among diffusion markers. For more details, see Baykara et al., Annals of Neurology 2016.
- Developer
- Marco Düring
- Lesion Type
- Microstructural damage
- Image Type
- Diffusion tensor imaging, MRI
- Website
- http://www.psmd-marker.com
Additional Information
- DOI Citation
- Pubmed Citation
- Dependencies
- FSL
- Availability
- Download
- License
- BSD 3-clause
- Academic Use
- Free
- Commercial Use
- Not Possible
- Development Status
- Stable
- Ongoing Support
- Yes
- Source Type
- Open Source
- Validation Status
- 2+ Independent Sample
- Automation
- Fully automated
- Intended Population
- Larger samples
- FAQ Link
- http://www.psmd-marker.com/faq/